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Professor Richard Costello

Registration No: 12647

Biography

A 1988 graduate of the Royal College of Surgeons in Ireland, Richard Costello underwent training at Beaumont Hospital and later at the Johns Hopkins University Hospital, Baltimore, USA. He is a Professor of Respiratory Medicine in Respiratory Medicine at the RCSI and Consultant Respiratory Physician at Beaumont Hospital working in asthma and neuromuscular conditions, including Duchenne’s muscular dystrophy. Professionally, he was Chair of Education at the European Respiratory Society and previously served the Royal College of Physicians as Vice President, Director of Research and National Specialist Director of Training in Respiratory Medicine. He has been President of the Irish Sleep Society, President of the European Board of Pulmonology, and is a Fellow of the European Respiratory Society. Academically, his work is focused on studying how digital technology can be used to optimise outcomes in patients with respiratory disease. He has copyrighted and licensed technology related to assessment of inhaler adherence. As Principal Investigator his work is supported by grants of over 15 Million from the EU, industry partners and the Health Research Board of Ireland. He has published over 180 research papers and he holds multiple patents and is the founder of a spin-out company Phyxiom.

Scope of practice

Airways diseases and Muscular Dystrophy Digital Medicine

Qualifications

MB, MD, FRCPI, FERS

Research & Scientific Contributions

Patents Adherence: “Method for Monitoring Adherence to Medication” EP17151063.9 “Method for Monitoring Adherence to Medication” US 16/477,379 Exacerbations: “Method and system to quantify and predict changes in lung function” GB2108919.8 INCA: “System and method for monitoring use of a device (INCA)” US10029056B2 “System and method for monitoring use of a device (INCA)” EP2890301B1 Publications Mac Hale E, Mulvey C, Greene G, Mokoka M, van Boven JF, Cushen B, Sulaiman, Murphy D, Heaney LG, Costello RW. Use of digital measurement of medication adherence and lung function to guide the management of uncontrolled asthma: The INCA Sun randomized clinical trial Lancet Respir Med. 2023 Jul;11(7):591-601. doi: 10.1016/S2213-2600(22)00534-3. McEnery T, Gough C, Costello RW. COVID-19: Respiratory support outside the intensive care unit. Lancet Respir Med. 2020. doi: 10.1016/S2213-2600(20)30176-4.. Shapiro CO, Proskocil BJ, Oppegard LJ, Blum ED, Kappel NL, Chang CH, Fryer AD, Jacoby DB, Costello RW, Drake MG. Airway Sensory Nerve Density Is Increased in Chronic Cough. Am J Respir Crit Care Med. 2021. doi: 10.1164/rccm.201912-2347OC. PMID: 32809840. A randomised controlled trial of the effect of a connected inhaler system on medication adherence in uncontrolled asthmatic patients. Moore A, Preece A, Sharma R, Heaney LG, Costello RW, Wise RA, Ludwig-Sengpiel A, Mosnaim G, Rees J, Tomlinson R, Tal-Singer R, Stempel DA, Barnes N. Eur Respir J. 2020 Dec 17:2003103. doi: 10.1183/13993003.03103-2020. O'Dwyer S, Greene G, MacHale E, Cushen B, Sulaiman I, Boland F, Bosnic- Anticevich S, Mokoka MC, Reilly RB, Taylor T, Ryder SA, Costello RW. Personalized Biofeedback on Inhaler Adherence and Technique by Community Pharmacists: A Cluster Randomized Clinical Trial. J Allergy Clin Immunol Pract. 2020 Feb;8(2):635-644. doi: 10.1016/j.jaip.2019.09.008. Heaney LG, Busby J, Bradding P, Chaudhuri R, Mansur AH, Niven R, Pavord ID, Lindsay JT, Costello RW; Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK). Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Nonadherence in Severe Asthma. Am J Respir Crit Care Med. 2019 doi: 10.1164/rccm.201806-1182OC. 1: Mokoka MC, McDonnell MJ, MacHale E, Cushen B, Boland F, Cormican S, Doherty C, Doyle F, Costello RW, Greene G. Inadequate assessment of adherence to maintenance medication leads to loss of power and increased costs in trials of severe asthma therapy. Results from a systematic literature review and modelling study. Eur Respir J. 2019 Mar 7. pii: 1802161. doi: 10.1183/13993003.02161-2018.. Drake MG, Scott GD, Blum ED, Lebold KM, Nie Z, Lee JJ, Fryer AD, Costello RW, Jacoby DB. Eosinophils increase airway sensory nerve density in mice and in human asthma. Science Transational Medicine. 2018 Sep 5;10(457). Cushen B, Sulaiman I, Greene G, MacHale E, Mokoka M, Reilly RB, Bennett K, Doyle F, van Boven JFM, Costello RW. The Clinical Impact of Different Adherence Behaviors in Patients with Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 Jun 15;197(12):1630-1633. Sulaiman I, Cushen B, Greene G, Seheult J, Seow D, Rawat F, MacHale E, Mokoka M, Moran CN, Sartini Bhreathnach A, MacHale P, Tappuni S, Deering B, Jackson M, McCarthy H, Mellon L, Doyle F, Boland F, Reilly RB, Costello RW. Objective Assessment of Adherence to Inhalers by Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 May 15;195(10):1333-1343. doi: 10.1164/rccm.201604-0733OC.Full Publication list Sulaiman I, Greene G, MacHale E, Seheult J, Mokoka M, D'Arcy S, Taylor T, Murphy DM, Hunt E, Lane SJ, Diette GB, FitzGerald JM, Boland F, Sartini Bhreathnach A, Cushen B, Reilly RB, Doyle F, Costello RW. A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma. Eur Respir J. 2018 Jan 4;51(1). pii: 1701126. doi: Blakey JD, Bender BG, Dima AL, Weinman J, Safioti G, Costello RW. Digital technologies and adherence in respiratory diseases: the road ahead. Eur Respir J. 2018 Nov 22;52(5):1801147. doi: 10.1183/13993003.01147-2018..
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Contact

Case Icon maryannthithai@beaumont.ie
Case Icon +353 1 809 3166